How good was your tank?
My 'up' time on the last kara raid I did was fairly low. This was due to being allowed to die a couple of times on AoE groups :/ but mainly due to me only burning SB at about 75% max due to me outgearing the tank by quite a way and holding back to avoid pulling aggro.
If aggro is an issue then I normally start with CoE ~ Immolate ~ check omen ~ spam away. I normally try for at least 5k threat buffer (10k on bosses). But it's all dependant on how good your tank is and how quickly he can build threat.
If threat isn't an issue then I normally CoE ~ spam on trash, or just spam (depends how I feel tbh
) and on bosses I CoE ~ Immo ~ Spam ~ trinks when available as long as I have a clear 15k to 20k buffer before popping trinks ... 3 x 6 to 7K crits can build threat very fast and I prefer to play it safe and not wipe than run the tank close on omen
The above applies to Kara/Gruuls/Maggy/VR as these are pretty much all I've raided so far.